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Search Results for " kras inhibitor-9 "

6

Compounds

Cat No. Product Name Synonyms Targets
T8756 KRAS inhibitor-9 DUN09716 Apoptosis , Ras
KRAS inhibitor-9 (DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. KRAS inhibitor-9 causes G2/M cell cycle arrest and induces apoptosis. KRAS ...
T6556 K-Ras(G12C) inhibitor 9 Raf
K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).
T64031 KRAS G12D inhibitor 9
KRAS G12D inhibitor 9 is a potent inhibitor of KRAS G12D. Among them, the RAS protein family is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 9 ...
T62981 KRAS inhibitor-17
KRAS inhibitor-17 (compound 3-9) is a potent inhibitor of KRAS G12C (IC50: 3.37 μM). KRAS inhibitor-17 exhibits p-ERK inhibition with IC50 = 9.25 μM in MIA PaCA-2 cells and >33.3 μM in A549 cells. KRAS inhibitor-17 has t...
T62478 SOS1-IN-9
SOS1-IN-9 is a potent inhibitor of SOS1 that acts on KRAS G12C-SOS1 (IC50: 116.5 nM).
T79808 KRAS G12C inhibitor 61 ERK
KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, reflected in an IC50 value of 9 nM. This inhibitor is applicable in the research of pancreatic, colorecta...
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